Development of Transdermal Patch for Electrically Controlled Insulin Release

At present, diabetic patients tend to increase steadily. In general, patients who are severe diabetes need regular insulin injections to keep their blood sugar levels within normal limits. However, the insulin injection method is inconvenient and can cause pain, especially in children. Due to these limitations, researchers developed various forms of insulin delivery systems, such as needle-free injection devices inhaled insulin, spray insulin, Insulin tablets, and insulin patches, etc. In addition, the controlled amount of insulin as the patient needs is another factor that makes the treatment effective and does not cause complications to the patient.

Therefore, this research aims to develop transdermal insulin patches to avoid problems of injections and make them more convenient to use. The insulin patch will be prepared from a polysaccharide cryogel that is non-toxic to users. Moreover, the amount of insulin release will be controlled by applying low- electrical voltage to help increase the efficiency of drug delivery into the body at a level and affects the control of the patient's sugar intake. The goal is to administer 10-20 units of insulin within 15 minutes.