Omic approach for biosurfactant production toward high value bioproduct development

Due to economic and population growth, these important factors stimulate the consumption of energy and needs of bio-based products. Therefore, looking for renewable energy and alternative energy as well as bio-precursors in the production of bio-based products is essential to accelerate this research and development. By adding value to agricultural waste, in addition to increasing income for farmers in the long run, Thailand gives great importance to implement the policy of renewable energy and the development of bio-based economies in order to sustain the country's development in a wealthy and sustainable way. Our research team has the intention and determination to develop innovation through the development of microbial platforms by applying high-potency yeast strains in the production of biochemicals and biofuels. To enhance innovation capability especially from agricultural waste utilization from the sugar cane, sugar and palm oil industries which is in line with the national strategy. By focusing on the key issues of the BCG Model, this project aims to increase the production efficiency of the biochemical industry using potent yeast for production of high value products in bio-industry. In the first research project, we put an emphasis on the use of high-potency yeast in the production of bio-surfactants, focusing on glycolipids (GLs) produced by non-pathogenic yeast in the Starmerella group. Its unique structure consisting of ω-hydroxy fatty acids can be used as an important precursor in the polymer industry as bioplastics, as well as food, pharmaceuticals, pharmaceuticals and bio-based materials as well as various high value substances. Because glycolipids are highly important in agriculture and industry, this research focuses on the utilization of glycolipids produced from different strains of yeasts for use as a precursor to the development of biologics in medicine. The glycolipids produced from the substrate can be used as an important biological surfactant. The yeast derived-biosurfactant has interesting biological properties such as the ability to inhibit pathogenic microorganisms. It also has a low cytotoxicity, environmentally friendly and biodegradable. At the end of this project, we expect to be able to scale up the production of yeast biosurfactants at the prototype factory level with a long-term goal for real applications in medicine, agriculture and other industries. The biosurfactants produced can also increase the value of waste materials and develop them into high-value substances in the bio-industry which is a large and very important industry of Thailand and the world