HBV Epidemic Control Using Time-Varying Sliding Mode Control Method

Hepatitis B virus (HBV) infection is one of the life-threatening diseases due to causing cirrhosis and liver cancer in the infected person. Setting the policy to control the HBV epidemic is an important issue that can be achieved by using feedback controller design procedure through the compartment model. In this article, the sliding mode controller with a time-varying sliding surface was utilized to set the multiple measures control policy for controlling the HBV epidemic. The stability of the control HBV epidemic system was examined. The simulation of the control system was conducted to confirm the feasibility of applying the time-varying sliding mode controller for setting the HBV control policy. The simulation results showed that the designed control policy could drive the target subpopulation to the desired levels. The convergence rate of the control HBV system could be improved. Thus, the time-varying sliding mode controller is a feasible approach to set the measures for controlling the HBV epidemic