Segmentation of lung lobes and lesions in chest CT for the classification of COVID-19 severity

บทความในวารสาร


ผู้เขียน/บรรณาธิการ

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กลุ่มสาขาการวิจัยเชิงกลยุทธ์


รายละเอียดสำหรับงานพิมพ์

รายชื่อผู้แต่งKhomduean, Prachaya; Phuaudomcharoen, Pongpat; Boonchu, Totsaporn; Taetragool, Unchalisa; Chamchoy, Kamonwan; Wimolsiri, Nat; Jarrusrojwuttikul, Tanadul; Chuajak, Ammarut; Techavipoo, Udomchai; Tweeatsani, Numfon

ปีที่เผยแพร่ (ค.ศ.)2023

Volume number13

Issue number1

นอก20452322

URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85178032777&doi=10.1038%2fs41598-023-47743-z&partnerID=40&md5=7ffc7195fc6a742e7df009abcf2f4a74

ภาษาEnglish-Great Britain (EN-GB)


ดูบนเว็บไซต์ของสำนักพิมพ์


บทคัดย่อ

To precisely determine the severity of COVID-19-related pneumonia, computed tomography (CT) is an imaging modality beneficial for patient monitoring and therapy planning. Thus, we aimed to develop a deep learning-based image segmentation model to automatically assess lung lesions related to COVID-19 infection and calculate the total severity score (TSS). The entire dataset consisted of 124 COVID-19 patients acquired from Chulabhorn Hospital, divided into 28 cases without lung lesions and 96 cases with lung lesions categorized severity by radiologists regarding TSS. The model used a 3D-UNet along with DenseNet and ResNet models that had already been trained to separate the lobes of the lungs and figure out the percentage of lung involvement due to COVID-19 infection. It also used the Dice similarity coefficient (DSC) to measure TSS. Our final model, consisting of 3D-UNet integrated with DenseNet169, achieved segmentation of lung lobes and lesions with the Dice similarity coefficients of 91.52% and 76.89%, respectively. The calculated TSS values were similar to those evaluated by radiologists, with an R2 of 0.842. The correlation between the ground-truth TSS and model prediction was greater than that of the radiologist, which was 0.890 and 0.709, respectively. ฉ 2023, The Author(s).


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อัพเดทล่าสุด 2024-20-03 ถึง 23:05