Electrochemical detection on electrowetting-on-dielectric digital microfluidic chip

Conference proceedings article

ผู้เขียน/บรรณาธิการ

กลุ่มสาขาการวิจัยเชิงกลยุทธ์

ไม่พบข้อมูลที่เกี่ยวข้อง

รายละเอียดสำหรับงานพิมพ์

รายชื่อผู้แต่ง: Karuwan C., Sukthang K., Wisitsoraat A., Phokharatkul D., Patthanasettakul V., Wechsatol W., Tuantranont A.

ผู้เผยแพร่: Elsevier

ปีที่เผยแพร่ (ค.ศ.): 2011

Volume number: 84

Issue number: 5

หน้าแรก: 1384

หน้าสุดท้าย: 1389

จำนวนหน้า: 6

นอก: 0039-9140

eISSN: 1873-3573

URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-79958136354&doi=10.1016%2fj.talanta.2011.03.073&partnerID=40&md5=2f65b460c91b41f1aaf999ef7597b6be

ภาษา: English-Great Britain (EN-GB)

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บทคัดย่อ

In this work, the use of three-electrode electrochemical sensing system with an electrowetting-on-dielectric (EWOD) digital microfluidic device is reported for quantitative analysis of iodide. T-junction EWOD mixer device was designed using arrays of 50-μm spaced square electrodes for mixing buffer reagent and analyte droplets. For fabrication of EWOD chips, 5-μm thick silver EWOD electrodes were formed on a glass substrate by means of sputtering and lift-off process. PDMS and Teflon thin films were then coated on the electrodes by spin coating to yield hydrophobic surface. An external three-electrode system consisting of Au working, Ag reference and Pt auxiliary wires were installed over EWOD electrodes at the end of T-junction mixer. In experiment, a few-microliter droplets of Tris buffer and iodide solutions were moved toward the mixing junction and transported toward electrochemical electrodes by EWOD process. A short processing time within seconds was achieved at EWOD applied voltage of 300 V. The analyte droplets mixed with different concentrations were successfully analyzed by cyclic voltametry. Therefore, the combination of EWOD digital microfluidic and electrochemical sensing system has successfully been demonstrated for rapid chemical analysis with minimal reagent consumption. © 2011 Elsevier B.V. All rights reserved.

คำสำคัญ

Digital microfluidic, Electrowetting-on-dielectric