Surface porosity and roughness of micrographite film for nucleation of hydroxyapatite
บทความในวารสาร
ผู้เขียน/บรรณาธิการ
กลุ่มสาขาการวิจัยเชิงกลยุทธ์
ไม่พบข้อมูลที่เกี่ยวข้อง
รายละเอียดสำหรับงานพิมพ์
รายชื่อผู้แต่ง: Asanithi P.
ผู้เผยแพร่: Wiley
ปีที่เผยแพร่ (ค.ศ.): 2014
วารสาร: Journal of Biomedical Materials Research Part A (1549-3296)
Volume number: 102
Issue number: 8
หน้าแรก: 2590
หน้าสุดท้าย: 2599
จำนวนหน้า: 10
นอก: 1549-3296
eISSN: 1552-4965
ภาษา: English-Great Britain (EN-GB)
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บทคัดย่อ
Heterogeneous nucleation of hydroxyapatite (HAp) can be facilitated by physical and chemical properties of material surface. In this article, we reported how effective surface porosity and roughness are for inducing nucleation of HAp crystal in simulated body fluid. Two types of micrographite film (MGF) prepared from assembly of micrographite flakes were used as seeds to induce HAp crystal: uncompressed (high surface porosity) and compressed (low surface porosity) MGFs. Compressed MGF was prepared by applying mechanical compression to the uncompressed MGF. Uncompressed and compressed MGFs have similar surface wettability with the water contact angles (θ) of 113° and 107°, respectively. The number density of HAp crystals on the uncompressed MGF was higher than that of the compressed MGF by a factor of 6. This result implied that surface porosity and roughness were more effective parameters for inducing HAp crystal than surface wettability. Uncompressed MGF also induced HAp nucleation better than a cover glass although the glass had high wettability (θ=64°). The effectiveness of uncompressed MGF on inducing HAp crystals was as high as that of the SiO2-coated Si substrate. Our finding suggests that we do not require to functionalize material surface to be an effective seed; a surface with pores or roughness of the right scale is enough. © 2013 Wiley Periodicals, Inc.
คำสำคัญ
micrographite film, porosity, roughness