Synthesis and characterization of artificial bone material using calcium from a natural source
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Publication Details
Author list: Chutong P., Poolthong N., Tongsri R.
Publisher: Trans Tech Publications
Publication year: 2015
Volume number: 659
Start page: 40
End page: 44
Number of pages: 5
ISBN: 9783038355526
ISSN: 1013-9826
eISSN: 1662-9795
Languages: English-Great Britain (EN-GB)
Abstract
Hydroxyapatite (HAp), with chemical formula of Ca10(PO4)6(OH)2,is one of the most wellknown biomaterials applied as a scaffold or a scaffold component in bone tissue engineering. Synthesis of this material using calcium from a natural source will be a good strategy for cost reduction. Waste cockle shells containing abundance of nearly pure calcium carbonate (CaCO3) are ideal sources of calcium. In this study, the waste cockle shells were converted to CaO nanoparticles using a simple chemical route. The CaO nanoparticle was used as a starting material to react with hydrous and anhydrous calcium hydrogen phosphate (CaHPO4) with calcium-to-phosphate (Ca/P) ratios in the range of 1.5-1.67 under a mechanochemical process. The synthesized products were characterized by X-ray diffraction technique and scanning electron microscope. The experimental results revealed that under the same reaction time the reaction using the dehydrated CaHPO4 yielded a mixture of HAp and residual CaHPO4 whereas the reaction using hydrated CaHPO4 (CaHPO4.2H2O) yielded a mixture of HAp and beta tricalcium phosphate (β-TCP). © (2015) Trans Tech Publications, Switzerland.
Keywords
CaO nanoparticles, Mechanochemical process
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