Molecular bionics – engineering biomaterials at the molecular level using biological principles
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Publication Details
Author list: Rodrํguez-Arco L., Poma A., Ruiz-P้rez L., Scarpa E., Ngamkham K., Battaglia G.
Publisher: Elsevier Ltd
Publication year: 2019
Volume number: 192
Start page: 26
End page: 50
Number of pages: 25
ISSN: 0142-9612
eISSN: 0142-9612
Languages: English-Great Britain (EN-GB)
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Abstract
Life and biological units are the result of the supramolecular arrangement of many different types of molecules, all of them combined with exquisite precision to achieve specific functions. Taking inspiration from the design principles of nature allows engineering more efficient and compatible biomaterials. Indeed, bionic (from bion-, unit of life and -ic, like) materials have gained increasing attention in the last decades due to their ability to mimic some of the characteristics of nature systems, such as dynamism, selectivity, or signalling. However, there are still many challenges when it comes to their interaction with the human body, which hinder their further clinical development. Here we review some of the recent progress in the field of molecular bionics with the final aim of providing with design rules to ensure their stability in biological media as well as to engineer novel functionalities which enable navigating the human body. ฉ 2018 Elsevier Ltd
Keywords
Biomedicine, Molecular bionics, Organic chemistry, Supramolecular Chemistry, Topology
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