Effects of chitosan and Tween 80 addition on the properties of nanofiber mat through the electrospinning
บทความในวารสาร
ผู้เขียน/บรรณาธิการ
กลุ่มสาขาการวิจัยเชิงกลยุทธ์
รายละเอียดสำหรับงานพิมพ์
รายชื่อผู้แต่ง: Boonpratum, Chalongwut; Naemchanthara, Patcharin; Limsuwan, Pichet; Naemchanthara, Kittisakchai
ผู้เผยแพร่: De Gruyter
ปีที่เผยแพร่ (ค.ศ.): 2022
Volume number: 22
Issue number: 1
หน้าแรก: 234
หน้าสุดท้าย: 248
จำนวนหน้า: 15
นอก: 1618-7229
eISSN: 1618-7229
ภาษา: English-Great Britain (EN-GB)
ดูในเว็บของวิทยาศาสตร์ | ดูบนเว็บไซต์ของสำนักพิมพ์ | บทความในเว็บของวิทยาศาสตร์
บทคัดย่อ
Chitosan (CS) with excellent biomedical properties was mixed with polyvinyl alcohol (PVA) to be used as the spinning solution. The spinning solutions with various concentrations of CS:PVA from 10:90% to 50:50% (v/v) were investigated. Tween 80 (T80) was added in the spinning solutions of CS and PVA. The nanofiber mats with and without T80 addition obtained from the spinning solutions by electrospinning technique were investigated and addressed. The results showed that the viscosity of the CS and PVA spinning solutions increased with increasing the CS concentration, whereas the viscosity decreased after T80 addition. The nanofiber mats with 10-30% CS concentrations were prepared successfully as a smooth surface and high dense nanofiber mat. The average diameter of the nanofiber decreased with increasing the CS concentration. The increase in the CS concentration of the nanofiber mat can increase the mechanical and antibacterial properties, whereas the wettability and drug release property were decreased. Moreover, the nanofiber mats with T80 addition had higher mechanical property and wettability than the nanofiber mats without T80 addition. Finally, the T80 addition can enhance hydrophilicity and promote the drug release property of the nanofiber mat. © 2022 Chalongwut Boonpratum et al., published by De Gruyter.
คำสำคัญ
Tween 80
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