Improved β-carotene production of Rhodotorula glutinis in fermented radish brine by continuous cultivation
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Author list: Malisorn C., Suntornsuk W.
Publisher: Elsevier
Publication year: 2009
Journal: Biochemical Engineering Journal (1369-703X)
Volume number: 43
Issue number: 1
Start page: 27
End page: 32
Number of pages: 6
ISSN: 1369-703X
eISSN: 1873-295X
Languages: English-Great Britain (EN-GB)
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Abstract
Fermentation kinetics of growth and β-carotene production by Rhodotorula glutinis DM28 in batch and continuous cultures using fermented radish brine, a waste generated from fermented vegetable industry, as a cultivation medium were investigated. The suitable brine concentration for β-carotene production by R. glutinis DM28 was 30 g l-1. Its growth and β-carotene production obtained by batch culture in shake flasks were 2.2 g l-1 and 87 μg l-1, respectively, while, in a bioreactor were 2.6 g l-1 and 186 μg l-1, respectively. Furthermore, its maximum growth rate and β-carotene productivity in continuous culture obtained at the dilution rate of 0.24 h-1 were 0.3 g l-1 h-1 and 19 μg l-1 h-1, respectively, which were significantly higher than those in the batch. Therefore, improved growth rate and β-carotene productivity of R. glutinis in fermented radish brine could be accomplished by continuous cultivation. © 2008 Elsevier B.V. All rights reserved.
Keywords
β-carotene
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