Recent applications of paper-based point-of-care devices for biomarker detection

บทความปริทัศน์

ผู้เขียน/บรรณาธิการ

กลุ่มสาขาการวิจัยเชิงกลยุทธ์

รายละเอียดสำหรับงานพิมพ์

รายชื่อผู้แต่ง: Suntornsuk, Worapot; Suntornsuk, Leena;

ผู้เผยแพร่: Wiley-VCH Verlag

ปีที่เผยแพร่ (ค.ศ.): 2020

วารสาร: ELECTROPHORESIS (0173-0835)

Volume number: 41

Issue number: 5-6

หน้าแรก: 287

หน้าสุดท้าย: 305

จำนวนหน้า: 19

นอก: 0173-0835

eISSN: 1522-2683

URL: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074567832&doi=10.1002%2felps.201900258&partnerID=40&md5=bdc49516f3c8856b69181d5041c08f2d

ภาษา: English-Great Britain (EN-GB)

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บทคัดย่อ

Detection of biomarkers is essential for diagnosis and prognosis of diseases for healthcare teams to provide timely appropriate treatments. Reliable, inexpensive, and sensitive devices are desirable to serve this purpose. Paper-based analytical devices (PADs) have gained enormous attention during the past decade as point-of-care devices for biomarker detection due to their simplicity, portability, and biocompatibility. Importantly, the devices highly comply with the WHO “ASSURED” concept (i.e. Affordable, Sensitive, Specific, User-friendly, Rapid and Robust, Equipment free, and Deliverable to end-users). Thus, PADs could be sustainably alternative tools for biomarker detection, especially in resources-constraint areas where budget, skillful operators, and health infrastructure are limited. First, this review introduces overviews of biomarkers, their detection and brief history of PADs. Second, description of common fabrication and detection techniques in PADs are provided. Then, it highlights recent state of the art technologies and applications of PADs for various biomarker detection published during 2018 to May 2019. Applications for tumor marker, cardiac and coronary heath disease, and metabolic disorder biomarker detection are tabulated and selected examples are described in details. Finally, it discusses the current challenges, advances, and novel applications of PADs. The review would be valuable for healthcare workers using PADs as cost-effective point-of-care devices for biomarker detection and for researchers working on future developments of the devices. © 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim

คำสำคัญ

lipids, paper-based point-of-care devices, prostate specific antigen, tumor markers